Item 7.01 Regulation FD Disclosure.

On November 5, 2007, Aeolus Pharmaceuticals, Inc. (“Aeolus”) provided an update on its drug development program and on November 7, 2007, Aeolus reported results of a pre-clinical study of AEOL 10150 for the treatment of mustard gas exposure.

Copies of the press releases issued by Aeolus on November 5, 2007 and November 7, 2007 announcing these events are attached as Exhibit 99.1 and 99.2, respectively, to this Current Report on Form 8-K.

Item 9.01. Financial Statements and Exhibits.

(c)  
Exhibits
 

 
 Exhbit 99.1  Press Release dated November 5, 2007
 Exhibit 99.2  Press Release dated November 7, 2007
 
 
SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this Report to be signed on its behalf by the undersigned thereunto duly authorized.

AEOLUS PHARMACEUTICALS, INC.

Date:  November 7, 2007
/s/ Michael P. McManus___________________
Michael P. McManus
Chief Financial Officer, Treasurer and Secretary