Item 8.01 Other Events.

American Society of Gene Therapy Presentation

On May 29, 2008, Mark Thornton, M.D., Ph.D., Senior Vice President of Product Development of GenVec, Inc. (“GenVec”), delivered a presentation to the American Society of Gene Therapy regarding TNFerade™ clinical development, including an update on long-term survival data from its Phase II clinical trial using TNFerade in patients with esophageal cancer. A copy of the press release regarding Dr. Thorton’s presentation is attached to this Current Report on Form 8-K as Exhibit 99.1 and is incorporated in this report by reference. A copy of Dr. Thornton’s presentation is attached to this Current Report on Form 8-K as Exhibit 99.2 and is incorporated in this report by reference.

American Society for Clinical Oncology (ASCO)

On May 31, 2008, GenVec issued a press release announcing a poster session at the annual meeting of the American Society for Clinical Oncology (ASCO) by study investigator Everett Vokes, M.D., University of Chicago. The poster presentation by Dr. Vokes, entitled “A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer (HNC),” reported study results. A copy of the press release is attached to this Current Report on Form 8-K as Exhibit 99.3 and is incorporated in this report by reference.

Statements contained in the exhibits to this Current Report, including those relating to future performance, development, results or events and other matters, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act. GenVec cautions that these forward-looking statements are subject to numerous assumptions, risks and uncertainties, which change over time. Factors that may cause actual results to differ materially from the results discussed in the forward-looking statements or historical experience include risks and uncertainties, including the failure by GenVec to secure and maintain relationships with collaborators; risks relating to certain of our product candidates being in early stages of development; uncertainties relating to clinical trials; risks relating to the commercialization, if any, of GenVec’s proposed product candidates; dependence on the efforts of third parties; dependence on intellectual property; and risks that we may lack the financial resources and access to capital to fund our operations. Further information on the factors and risks that could affect GenVec’s future results are contained in GenVec’s filings with the U.S. Securities and Exchange Commission (SEC), which are available at www.sec.gov, including in the risk factors section of GenVec’s Annual Report on Form 10-K. These forward-looking statements speak only as of the date of the exhibits to this Current Report in which they appear, and GenVec assumes no duty to update forward-looking statements.


Item 9.01 Financial Statements and Exhibits.

(d)
Exhibits
   
99.1  
GenVec, Inc. press release dated May 29, 2008.
   
99.2
GenVec, Inc. presentation dated May 29, 2008.
   
99.3
GenVec, Inc. press release dated May 31, 2008.


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 
GENVEC, INC.
     
Date: June 2, 2008
By:  
/s/ Douglas J. Swirsky
   
 Douglas J. Swirsky
   
 Senior Vice President, Chief Financial Officer,
 Treasurer and Corporate Secretary

 
EXHIBIT INDEX
 
GenVec, Inc. press release dated May 29, 2008.
   
99.2
GenVec, Inc. presentation dated May 29, 2008.
   
99.3
GenVec, Inc. press release dated May 31, 2008.