On March 18, 2008, SciClone Pharmaceuticals, Inc., a Delaware corporation (the “Company”) granted to Friedhelm Blobel, Ph.D., the Company’s President, Chief Executive Officer and a member of the Company’s Board of Directors, an option to purchase 300,000 shares of the Company’s common stock under the Company’s 2005 Equity Incentive Plan at an exercise price per share equal to the closing price on the NASDAQ Global Market of a share of the Company’s common stock on March 18, 2008 (the “Option”). The Option has a term of 10 years and is a nonstatutory option. The Option will vest, provided Dr. Blobel is still employed by the Company, upon the Company’s common stock trading publicly after March 17, 2008 for at least 30 consecutive calendar days at or greater than a target closing price per share as reported on the NASDAQ Global Market (a “Trading Price Goal”), of (a) $4.50 on or before June 2, 2009 for 50,000 shares, (b) $6.00 on or before June 2, 2010 for 50,000 shares, (c) $8.00 on or before June 2, 2011 for 50,000 shares, (d) $10.00 on or before June 2, 2012 for 50,000 shares, (e) $12.00 on or before June 2, 2013 for 50,000 shares, and (f) $14.00 on or before June 2, 2014 for 50,000 shares, each price as adjusted for stock dividends, stock splits or similar changes in the Company’s capital structure. If a Trading Price Goal is not achieved on or before the respective target dates (06/02/2009, 06/02/2010, 06/02/2011, 06/02/2012, 06/02/2013 and 06/02/2014), the corresponding portion of the Option will not vest and will terminate upon such date.

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SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.