Item  2.02 Results of Operations and Financial Condition.

On February 22, 2007, Targacept, Inc. issued a press release relating to its financial results for the fourth quarter and year ended December 31, 2006. The full text of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K.

The information in this Current Report on Form 8-K (including Exhibit 99.1) shall not be deemed to be “filed” for purposes of Section 18 of the Securities and Exchange Act of 1934 (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such a filing.

 

Item 9.01 Financial Statements and Exhibits.

 

  (d) Exhibits

The following exhibit is furnished with this report:

 

Exhibit Number

  

Description

99.1    Press release dated February 22, 2007

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

     TARGACEPT, INC.
Date: February 22, 2007   

/s/ Alan A. Musso

   Alan A. Musso
   Vice President, Chief Financial Officer, Secretary and Treasurer

EXHIBIT INDEX

 

Exhibit Number

  

Description

99.1

   Press release dated February 22, 2007