Item  8.01 Other Events
Item 9.01 Financial Statements and Exhibits
SIGNATURES
EXHIBIT INDEX
EX-99.1: PRESS RELEASE

Table of Contents

Item 8.01 Other Events.
On September 22, 2008, Vion Pharmaceuticals, Inc. announced that it had entered into an agreement with the Institut Paoli- Calmettes in Marseille, France to conduct a multi-center Phase I/II clinical trial of laromustine (Cloretazine® (VNP40101M)) with remission-induction therapy in patients aged 18-60 with previously untreated acute myelogenous leukemia (AML) and a poor prognosis based on their cytogenetic profile. The Institut Paoli-Calmettes will be leading the study for the French cooperative group GOELAMS (Groupe Ouest Est d’Etude des Leucémies et Autres Maladies du Sang). A copy of the press release is attached hereto as Exhibit 99.1 and incorporated by reference herein.
Item 9.01 Financial Statements and Exhibits.
     (d) Exhibits.
Exhibit 99.1    Press release dated September 22, 2008.