declineIt is always interesting to see a stock decline, especially if it's a good company with rather bright prospects of recovery. Today we will take a look at the biggest losers of the week, which stocks are selling under $5 per share. As we all know, such companies are usually very volatile and today's decline might mean tomorrow's profits. But not for all of them...

The biggest loser, among the ones we will cover, was Isolagen, Inc. (AMEX: ILE, ILE message board) , with a share price decline of nearly 29% since May 29, 2008. After a notice of non-compliance with listing requirements, the anaesthetic and therapeutic development stage company has already presented its plan of compliance to AMEX. However, on May 30, 2008, the Exchange discarded their plan as having no merit for Isolagen's recovery. The company has a Phase III clinical trial product, however it isn't likely they will be able to come out of development stage.

Another company in danger of delisting is Medicure Inc. (AMEX: MCU) , with a share price decline of 16% since last week. This biopharmaceutical company received notice from AMEX, on May 30, 2008, for non-compliance with listing standards. It was about time, since the company has continually incurred losses from operations for at least five years. The company still has a chance to stay on AMEX by providing a viable plan of recovery, however it's more likely that we will be seeing this company only on Toronto Stock Exchange in the near future (TSX: MPH).

Peace Arch Entertainment Group Inc. (AMEX: PAE) , an integrated global entertainment company, announced on June 4, 2008, orders for 58 episodes of various non-fiction programs that will be later offered to various cable networks. After continuous decline for a whole week, the company's shares lost nearly 14% of their worth, so such an announcement might evoke some positive stock reaction. However the share price has been on a downtrend for the last year, so such a minor event isn't likely to trigger the trend reversal.

Crystallex International Corp. (AMEX: KRY) is more of the loser of the day. The company's shares plummeted nearly 10% on June 4, 2008, after its president and CEO, Gordon Thompson, resigned in order to "pursue personal interests". The company has already appointed Robert Fung as Executive chairman and CEO and Robert Crombie as president. Hopefully they will manage to reverse the wild ride down that their stock has had for a whole year.

ADVENTRX Pharmaceuticals, Inc. (AMEX: ANX) had a bumpy ride, and their stock ended up losing nearly 9% over the week. The company announced on June 3, 2008, achievements in Phase 2 clinical study of ANX-510 drug, also known as CoFactor(R), at the 2008 American Society of Clinical Oncology Annual Meeting. The drug is dedicated to the treatment of advanced breast cancer. The announcement had no positive reaction on the share price. However, the downtrend at least stopped for while.